How L-Arginine works: What The Medical World Says

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How L-Arginine works: What The Medical World Says

For long over a decade, Synergy Worldwide has known the benefits and how L-Arginine works. A chemical building block, more commonly called an amino acid. L-Arginine is obtained through the diet and is found in common foods including red meat, poultry, fish, and dairy products.


How L-Arginine works?

As L-Arginine is crucial for the body to make proteins, it can also be made in laboratories and used as medicine. There are several health reasons for this. Once in the body, L-Arginine is converted into a chemical called nitric oxide, which causes blood vessels to open wider for better blood flow. As well as improving blood flow, L-Arginine also helps create the release of insulin, the growth hormone and other substances.


Benefits of L-Arginine

There are several significant long-term health benefits associated with L-Arginine. These can be achieved through increasing the consumption of certain food groups such as poultry, fish and dairy products, taking medicine or taking a daily herbal supplement.


Research shows that L-Arginine can:

Reduce high blood pressure

Arginine-derived nitric oxide is created by the endothelial cells lining your arteries, and it is now known to be the principal blood pressure regulator of the body.

Once produced and released by the endothelium, nitric oxide causes the arterial smooth muscles making up the vessel walls to relax. This enlarges the interior diameter of the artery and ultimately lets more blood flow through.

One study, first presented in November 1997 at the American Heart Association’s 70th Scientific session and later published in Circulation, looked at patients ranging in age between thirty and seventy and suffering mild to moderate hypertension (i.e. blood pressure greater than 160/90 mm Hg). The researchers found that after taking an oral arginine supplement of 2,000 milligrammes per day, their blood pressure lowered significantly.[1]

Another study that appeared in the Journal of the American College of Cardiology looked at fourteen patients in Italy newly diagnosed with borderline high blood pressure. The researchers found that it took only two grammes a day of L-Arginine administered orally for a week to trigger nearly twenty point drops in systolic blood pressure. This rapid improvement was attributed to L-Arginines’ ability to improve endothelial function.[2]


Lower cholesterol

L-Arginine works also to benefit individuals with high cholesterol. In a study, Stanford researchers showed that arginine reduced the tendency of blood platelets to clump, potentially lessening the risk of heart attacks and strokes in people with elevated cholesterol.

An earlier study at Sinai Hospital in Baltimore found that two weeks of arginine therapy reduced total and LDL cholesterol but had no effect on HDL cholesterol in healthy elderly volunteers.


Relieve angina

A Mayo Clinic study found that patients with early heart disease who took arginine supplements for six months had better blood flow to the heart and less angina compared with a placebo group. Scientists in Poland also found that arginine increased the exercise capacity of patients with angina who had had a heart attack.[3]


Boost Immunity

Preliminary evidence suggests that the supplement (arginine) may also boost immunity, reverse impotence, and forestall many of the complications of diabetes. For example, it is known that the immune system can kill infectious microbes, from Salmonella to Chlamydia, by emitting a small amount of nitric oxide.

Several studies have now shown that arginine supplements can activate the immune system and spur wound healing after surgery or trauma.


How L-Arginine Works to Help Erectile Dysfunction

As the amino acid arginine promotes natural nitric oxide production in the body, by enhancing nitric oxide and subsequent cyclic GMP synthesis, arginine enlarges blood vessels in the corpus cavernosum that can lead to enhanced sensation and penile erection.

Arginine is given to prize race horses to increase their number of sexual encounters, and to improve the quality of their sperm.

Arginine is similar to Viagra in as much as it is effective by boosting cyclic GMP levels through the production of nitric oxide. The longer these cyclic GMP levels are maintained, the more chance of achieving and maintaining an erection. One benefit of using L-Arginine is that it is more cost-effective than Viagra. Between 6 and 12 grammes, a day of arginine is the dose of arginine estimated to achieve enhanced sexual function.

Find out how L-Arginine works for you with ProArgi


In people with diabetes, arginine blood levels are often reduced. Some evidence indicates that arginine can slow the progression of atherosclerosis in those with the disease. It should not, however, be taken by people with diabetic retinopathy.


Medical Support

From various corners of the medical world, support has been given for the use of L-Arginine.

“In the field of medicine and health, it is one of the revolutions of our time. the discovery that the amino acid L-Arginine may be a ‘magic bullet’ for the cardiovascular system. A virtual arterial cleanser, arginine helps eliminate blockage and maintains blood flow,” said Woodson Merrell, M.D, Columbia University Medical School.

Harold Bloomfield, M.D., went on to say that “L-Arginine is a safe, effective, and inexpensive means of self-care that boosts immunity, sexual potency, and general well-being.”

A host of support has been given towards the use of L-Arginine with regards to the specific benefits it provides to circulation.

L-Arginine supplementation has been found to reduce pathological increases in the thickness of plaque lined vessel walls in people with elevated cholesterol and atherosclerosis.

In his best-selling book, “The Cardiovascular Cure,” the author John Cooke, PhD states that arginine-derived nitric oxide (ADNO) has several benefits for the body, health and overall well-being:

  • It keeps blood vessels pliable and elastic
  • It keeps blood flowing smoothly
  • It keeps platelets calm and prevents them from sticking to the vessel wall
  • It keeps white blood cells calm and prevents them from sticking to the vessel wall
  • It reduces growth and multiplication of muscle cells that thicken the vessel wall
  • It slows plaque growth and suppresses atherosclerosis
  • It may melt away plaque that already exists


Synergy Products

Synergy provides supplements through its range of products that use natural supplements and place health as their number one priority. Helping people for over a decade now to over 28 countries, its popular ProArgi-9+ has  L-Arginine as one of its primary ingredients. It contains five essential vitamins: Vitamin C, Vitamin D3, Vitamin K, Vitamin B6 and Vitamin B12. ProArgi-9+  was researched by three American scientists who were awarded the Nobel Prize in 1998 for discovering its powerful health benefits.

For more information on L-Arginine and its benefits or any of our products and services, contact me today for help.



1.& 2. Robert Fried, Ph.D., and Woodson C. Merrell, M.D., The Arginine Solution (Warner Books, 1999)

3. Robert Fried, Ph.D., and Woodson C. Merrell, M.D., The Arginine Solution (Warner Books, 1999)

How L-Arginine works: What The Medical World Says

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